ARBOR分析/组蛋白去甲基酶（HDM）荧光活性试剂盒/K010-F1/F1-免疫在线蚂蚁淘旗下平台

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商品详细ARBOR分析/组蛋白去甲基酶（HDM）荧光活性试剂盒/K010-F1/F1

ARBOR分析/组蛋白去甲基酶（HDM）荧光活性试剂盒/K010-F1/F1

商品编号： K010-F1

品牌： arborassays

市场价： ¥7000.00

美元价： 4200.00

产地：美国(厂家直采)

公司：

产品分类：其它检测试剂盒

公司分类： Other_kits

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

MultiSpecies

USE-MeasureallHDMs;LSD1andJumonjitype
SAMPLE-Lysates,PurifiedEnzymeSystems
SAMPLES/KIT-89inDuplicate
CALIBRATED-MeasureFormaldehydeProducedbyDemethylation
STABILITY-Stable4˚CLiquidReagents

TheDetectX^®UniversalHistoneDemethylase(HDM)FluorescentActivitykitallowsallknownHDMstobemeasuredinlow,mediumandhighthroughputfashion.RunthedemethylasereactionandaftercompletionsimplyaddthesuppliedFormaldehydeDetectionReagenttoeachwellandreadthefluorescentsignalgenerated.Excitationat450nm/Emissionat510nmusinganadjustablegainplatefluorimeter.

Formaldehydeisacommonbyproductformedinoxidativedemethylation.Examplesofformaldehyde-producingenzymesincludehistonedemethylases(HDMs)thatmodifymethylatedhistones.Lysine-specificHDMswerefirstdiscoveredin2004andarecurrentlyamongthemostactivelystudiedformaldehyde-producingenzymes.HDMscatalyzethesite-specificdemethylationofmethyl-lysineresiduesinhistonestodynamicallyregulatechromatinstructure,geneexpression,andpotentiallyothergenomicfunctions.Atpresent,therearetwoknownclassesofHDMs:theflavinadeninenucleotide(FAD)-dependentLysineSpecificDemethylase1(LSD1)familyandtheFe(II)-dependentJumonjiC(JmjC)family.AlthoughtheLSD1andJmjCHDMsemploydifferentcofactorsandcatalyticmechanisms,bothproduceformaldehydeasabyproductofthedemethylationreaction.DespitetheirBIOLOGicalimportance,HDMshaveprovendifficulttoquantitativelyassayowingtotheirrelativelylowturnovernumbers,hinderingourunderstandingoftheirkineticproperties,substratespecificities,andreactionmechanisms.

LSD1 Inhibition by Tranylcypromine

DataReductionTemplatebyMyAssays

品牌介绍

ARBOR ASSAYS自1982年以来，Arbor Assays公司的创始人和顶尖科学家一直在研究和开发高质量的分析工具。我们是在制造fda调节的体外诊断产品以检测人类疾病的过程中成长起来的。Our philosophy is to build the highest quality detection and immunoassay products for clinically important biomolecules. We build robust immunoassay and enzyme activity kits to quantitate biomolecules in biological matrices.品牌货号名称规格ARBOR ASSAYSH053-H1DHEA-S Measurements Made Simple1 PlateARBOR ASSAYSH053-H5DHEA-S Measurements Made Simple5 PlateARBOR ASSAYSH067-H1Glutathione (GSH) Colorimetric Cuvette Detection Kit1 PlateARBOR ASSAYSH067-H5Cortisol EIA Kit5 PlateARBOR ASSAYSH066-H1Glutathione (GSH) Colorimetric Cuvette Detection Kit1 PlateARBOR ASSAYSH066-H5Cortisol EIA Kit5 PlateARBOR ASSAYSK015-F1Acetylcholinesterase Fluorescent Activity Kit2 PlateARBOR ASSAYSK052-C1Aldosterone Chemiluminescent Immunoassay Kit1 PlateARBOR ASSAYSK052-C5Aldosterone Chemiluminescent Immunoassay Kit 5 PlateARBOR ASSAYSK052-H1Aldosterone Chemiluminescent Immunoassay Kit1 PlateARBOR ASSAYSK052-H5Aldosterone EIA Kit5 PlateARBOR ASSAYSK044-C1Allopregnanolone EIA Kit1 PlateARBOR ASSAYSK044-C5Allopregnanolone Chemiluminescent Immunoassay Kit5 PlateARBOR ASSAYSKO44-H1Glutathione (GSH) Colorimetric Cuvette Detection Kit1 PlateARBOR ASSAYSKO44-H5Cortisol EIA Kit5 Plate

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