
- MultiSpecies
- USE-MeasureHemoglobinin30Minutes
- SAMPLE-WB,RBCs,SerumandPlasma
- SAMPLES/KIT-88inDuplicate
- SENSITIVE-Measureaslittleas20µg/mL
- STABILITY-Stable4˚CLiquidReagents
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TheDetectX®HemoglobinDualRangeColorimetricDetectionkitusesasinglereactionsolutionthatisstableat4°C,isnotlightsensitive,anddoesnotcontaindangerouschemicals.Allformsofhemoglobinarerapidlyconvertedtoasinglestableformthatismeasuredphotometricallyat560-580nm.Ahumanhemoglobinstandardisprovidedtogenerateastandardcurvefortheassay.Availableastwoformats–RegularFormatforWholeBloodandRBCs,andaHighSensitivityFormatforPlasma&Serum.
Hemoglobin(Hgb)isanerythrocyteproteincomplexcomprisedoftwosetsofidenticalpairsofsubunits,eachofwhichbindaniron-prophyringroupcommonlycalledheme.Generallycontainingtwoalphaoralpha-likeglobinchains,theremainingsubunitsmaybebeta,gamma,deltaorepsilon,orinthecaseofinfants,fetalhemoglobinthatisreplacedduringthefirstyearoflife.Hemebindsandreleasesoxygenorcarbondioxideinresponsetoslightchangesinlocalgastension.Freeoxygenorcarbondioxideboundbyonehemegroupfacilitatessubsequentbindingbytheotherhemegroupsinagivenhemoglobinmolecule.SubtlechangesinpHalsoregulatehemoglobinaffinityforfreegases,resultinginahighlevelofhemostaticcontrol.Hemoglobinvaluesareassociatedwithavarietyofconditionsrangingfromanemias(lowHgb),erythrocytosis(highHgb),thalassemias(aberrantchainsynthesis),andsicklingdisorders(abnormalcomplexshape).
DataReductionTemplatebyMyAssays